Precise measurements
During the last years, ExCard Research has conducted precise
and efficient measurements of the QT-interval on thousands of ECGs
in the course of numerous clinical trials, including thorough QT/QTc
trials.
Qualifications of ECG readers
All interval measurements are performed by highly trained physician
electrocardiographers (physicians). All ECG readers are experienced
in analyzing study ECGs from pharmacological studies, including
definitive QT studies.
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Measurements and ECG interpretation are checked and verified by
cardiologists. One reader analyses all ECG recordings from a particular
subject.
All ECG readers undergo an intensive training course before trial
ECGs are evaluated. The analysis of blinded ECGs ensures that metrics
are available to demonstrate any intra- and interreader variability.
To ensure consistency during the course of a trial, a subgroup of
skilled readers is appointed prior to the start of the study. |